anti-Adrenocorticotropic Hormone (ACTH) antibody

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Antigène:	Adrenocorticotropic Hormone (ACTH)
Clonalité:	Monoclonal (57)
Application:	Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Reactivité:	Human, Rat
Hôte:	Mouse
Quantité:	0.2 mg (1.0 mg/ml) (Alternatives)
Prix:	Produit non disponible pour cette région.
Numéro du produit:	ABIN110701
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Antigène	Adrenocorticotropic Hormone (ACTH)
Immunogène	Keyhole Limpet Haemocyanin conjugated human ACTH (1-17)
Reactivité	Human, Rat
Clonalité	Monoclonal
Format	Purified
Isotype	IgG1 »Anticorps secondaires correspondants
Description	ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.
Clone	57
Hôte	Mouse
Specificité	This antibody recognises 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally- occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. It does not recognise 17-39 ACTH (CLIP).

Application	Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Indications d'application	Immunohistochemistry on formalin fixed, paraffin embedded sections. ELISA (sandwich and simple). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration	1.0 mg/ml
Purification	Protein A affinity chromatography
Buffer	PBS, pH 7.2, containing 0.09% sodium azide
Stock	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Domaine de recherche	Hormones
Restrictions	For Research Use only