Interferon gamma anticorps

N° du produit ABIN1107642

Détail du produit anti-Interferon gamma anticorps

Antigène: Interferon gamma (IFNG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Recombinant IFNG / Interferon gamma Western Blot and ELISA. Other species not tested.

Purification: Affinity Chromatography on Protein A

Immunogène: Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)

Clone: 3F1E3

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFNG / Interferon gamma (IFNG Produits)

Synonymes: anticorps IFG, anticorps IFI, anticorps IFN-g, anticorps Ifg, anticorps IFNG2, anticorps IFN-gamma, anticorps IFN-G, anticorps IFNG, anticorps IFNgamma, anticorps TCRalpha, anticorps INF-G, anticorps ifng, anticorps interferon gamma, anticorps interferon, gamma 1-2, anticorps IFNG, anticorps Ifng, anticorps ifng1-2

Sujet: Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-γ strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.Synonyms: IFN-gamma, gamma IFN

ID gène: 3458

NCBI Accession: NP_000610

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy