SEMA7A anticorps

N° du produit ABIN110773

Détail du produit anti-SEMA7A anticorps

Antigène: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SEMA7A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Specificité: The antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ion exchange chromatography

Pureté: > 95 % (by SDS-PAGE)

Immunogène: HPB-ALL human T cell line

Clone: MEM-150

Isotype: IgM

Information d'application

Indications d'application: Flow Cytometry. Immunoprecipitation. Western Blotting under non reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SEMA7A

Antigène: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Autre désignation: CD108 / SEMA7A (SEMA7A Produits)

Synonymes: anticorps 2900057C09Rik, anticorps CDw108, anticorps H-Sema-L, anticorps M-Sema-L, anticorps Semal, anticorps CD108, anticorps H-SEMA-K1, anticorps JMH, anticorps SEMAK1, anticorps SEMAL, anticorps sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A, anticorps semaphorin 7A (John Milton Hagen blood group), anticorps Sema7a, anticorps SEMA7A

Sujet: CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors plexin C1 and b1 integrins.Synonyms: JMH blood group antigen, John-Milton-Hargen human blood group Ag, SEMAL, Semaphorin-7A, Semaphorin-K1, Semaphorin-L

ID gène: 8482

NCBI Accession: NP_001139501

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size