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EpCAM anticorps (FITC)

EPCAM Reactivité: Humain IF, IHC (p), IHC (fro) Hôte: Souris Monoclonal HEA125 FITC
N° du produit ABIN111179
  • Antigène Voir toutes EpCAM (EPCAM) Anticorps
    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
    Reactivité
    • 294
    • 84
    • 35
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 161
    • 143
    • 19
    • 1
    Souris
    Clonalité
    • 206
    • 114
    • 2
    Monoclonal
    Conjugué
    • 157
    • 21
    • 19
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
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    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EpCAM est conjugé à/à la FITC
    Application
    • 222
    • 191
    • 126
    • 116
    • 93
    • 33
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    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    The Ep-CAM (HEA125) antibody recognizes the epithelial cell adhesion molecule Ep-CAM (also described as 17-1A antigen or EPG34). This antigen is widely expressed on cells of epithelial origin and tumors derived therefrom. HEA125 represents an excellent marker to discriminate epithelial from mesothelial structures. The antigen has been detected in all carcinoma types tested (18 different origins). A subset of squamous cell carcinoma is negative. Tested Reactivities on Cultured Cell Lines: All carcinoma cell lines tested so far, particularly strong reaction with colon carcinoma cell lines (HT-29, WiDr, SW1116). Polypeptide reacting: Mr 40,000 human epithelium-specific cell surface glycoprotein (Ep-CAM).Polypeptide reacting:
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein A
    Immunogène
    HT-29 colon carcinoma cell line
    Clone
    HEA125
    Isotype
    IgG1
    Top Product
    Discover our top product EPCAM Anticorps primaire
  • Indications d'application
    Immunofluorescence Microscopy. Cell Sorting, Cytological Material. Immunohistochemistry on Frozen Sections and Paraffin-Embedded Sections. With Paraffin embedded sections, protease pretreatment is required prior to antibodyapplication. Working Dilution: Dilute at least 1/10 with PBS, pH 7.4 for Immunohistochemicalapplication. Incubation Time: 1 h at RT.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    3.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
    Autre désignation
    CD326 / EPCAM / TACSTD1 (EPCAM Produits)
    Synonymes
    anticorps DIAR5, anticorps EGP-2, anticorps EGP314, anticorps EGP40, anticorps ESA, anticorps HNPCC8, anticorps KS1/4, anticorps KSA, anticorps M4S1, anticorps MIC18, anticorps MK-1, anticorps TACSTD1, anticorps TROP1, anticorps ECS-1, anticorps ECS1, anticorps ESA1, anticorps M17S1, anticorps EGP, anticorps Ep-CAM, anticorps sb:cb6, anticorps tacstd, anticorps wu:fj17g02, anticorps zgc:110304, anticorps zgc:77119, anticorps tacstd1, anticorps MGC80540, anticorps EPCAM, anticorps egp, anticorps ksa, anticorps m4s1, anticorps mk-1, anticorps cd326, anticorps egp40, anticorps mic18, anticorps trop1, anticorps ep-cam, anticorps hegp-2, anticorps co17-1a, anticorps ga733-2, anticorps CD326, anticorps Egp314, anticorps EpCAM1, anticorps GA733-2, anticorps Ly74, anticorps Tacsd1, anticorps Tacstd1, anticorps gp40, anticorps epithelial cell adhesion molecule, anticorps flotillin 2, anticorps epithelial cell adhesion molecule S homeolog, anticorps EPCAM, anticorps FLOT2, anticorps epcam, anticorps epcam.S, anticorps Epcam
    Sujet
    Epithelial Cell Adhesion Molecule (EpCAM) is a 40 kDa cell surface antigen. This antigen has been identified independently by a number of groups, and has been known by a variety of names. Several monoclonal antibodies have been raised against EpCAM, many of which have been described as tumour specific molecules on carcinomas. EpCAM is a Type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells. EpCAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumour cells, and de novo expression being seen in dysplastic squamous epithelium.Synonyms: Adenocarcinoma-associated antigen, EGP314, Ep-CAM, Epithelial cell adhesion molecule, Epithelial glycoprotein 314, GA733-2, KS 1/4 antigen, KSA, M1S2, M4S1, MIC18, Major gastrointestinal tumor-associated protein GA733-2, TROP1, Trop-1, Tumor-associated calcium signal transducer 1
    ID gène
    4072
    NCBI Accession
    NP_002345
    UniProt
    P16422
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