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Osteoprotegerin anticorps (N-Term)

TNFRSF11B Reactivité: Humain WB, EIA Hôte: Souris Monoclonal OPG-13 unconjugated
N° du produit ABIN114693
  • Antigène Voir toutes Osteoprotegerin (TNFRSF11B) Anticorps
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-39, N-Term
    Reactivité
    • 60
    • 21
    • 18
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 50
    • 11
    • 2
    • 1
    Souris
    Clonalité
    • 54
    • 10
    Monoclonal
    Conjugué
    • 42
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteoprotegerin est non-conjugé
    Application
    • 48
    • 29
    • 26
    • 18
    • 11
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    The Anti Human Osteoprotegerin, Clone: OPG-13 is a mouse monoclonal antibody against synthetic peptide of Human Osteoprotegerin.
    Purification
    Affinity chromatography on protein G
    Immunogène
    Synthetic OPG peptide that comprises AA21 to AA39 homologous with human osteoprotegerin (N-terminal C has been added to the peptide)
    Clone
    OPG-13
    Isotype
    IgG1
    Top Product
    Discover our top product TNFRSF11B Anticorps primaire
  • Indications d'application
    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.1 mL of deionized water
    Concentration
    1.0 mg/mL
    Buffer
    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Date de péremption
    6 months
  • Antigène
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Autre désignation
    Osteoprotegerin / TNFRSF11B (TNFRSF11B Produits)
    Synonymes
    anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps OCIF, anticorps OPG, anticorps TR1, anticorps Opg, anticorps ocif, anticorps opg, anticorps tr1, anticorps TNF superfamily member 11, anticorps TNF receptor superfamily member 11b, anticorps tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin), anticorps TNF receptor superfamily member 11B, anticorps tumor necrosis factor receptor superfamily member 11b S homeolog, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps TNFSF11, anticorps TNFRSF11B, anticorps Tnfrsf11b, anticorps tnfrsf11b.S
    Classe de substances
    Chemical
    Sujet
    Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
    ID gène
    4982
    NCBI Accession
    NP_002537
    UniProt
    O00300
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