Gastrin anticorps

N° du produit ABIN115354

Détail du produit anti-Gastrin anticorps

Antigène: Gastrin (GAST)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
Cellular Localization: Cytoplasmic

Purification: Purified

Immunogène: Recombinant Gastrin conjugated to KLH.

Information d'application

Indications d'application: Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: containing sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: Gastrin (GAST Produits)

Synonymes: anticorps GAS, anticorps Gas, anticorps PPG34, anticorps GAST, anticorps gastrin, anticorps GAST, anticorps Gast

Sujet: Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST

ID gène: 2520

NCBI Accession: NP_000796

UniProt: P01350