FLT1 anticorps (C-Term)
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- Antigène Voir toutes FLT1 Anticorps
- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FLT1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody reacts with a 180 kDa protein, known as Flt-1/Vascular Endothelial Growth Factor Receptor 1. Cellular localization: cytoplasmic.
- Purification
- Purified
- Immunogène
- A synthetic peptide derived from the C-terminus of the Flt-1 precursor of human origin
- Top Product
- Discover our top product FLT1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on Formalin-Fixed Paraffin Embedded Tissues: Use a dilution of1/50-1/100 in an ABC method (incubation period of 30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0, prior to immunostaining. Recommended Positive Control: Angiosarcoma. Also useful for Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
- Autre désignation
- VEGFR-1 / Flt-1 (FLT1 Produits)
- Synonymes
- anticorps FLT, anticorps FLT-1, anticorps VEGFR-1, anticorps VEGFR1, anticorps FLT1, anticorps flt1b, anticorps sFlt1, anticorps AI323757, anticorps Flt-1, anticorps fms related tyrosine kinase 1, anticorps FMS-related tyrosine kinase 1, anticorps vascular endothelial growth factor receptor 1, anticorps fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), anticorps FMS-like tyrosine kinase 1, anticorps vascular endothelial growth factor receptor-1, anticorps FLT1, anticorps Flt1, anticorps CpipJ_CPIJ012087, anticorps flt1, anticorps FLT-1
- Sujet
- VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. Flt-1 is a cell membrane receptor kinase. Flk-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
- ID gène
- 2321
- NCBI Accession
- NP_001153392
- UniProt
- P17948
- Pathways
- Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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