CXCL1 anticorps (Biotin)

N° du produit ABIN115927

Détail du produit anti-CXCL1 anticorps (Biotin)

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Recognises Murine KC.

Purification: Affinity chromatography.

Immunogène: Highly pure (>98%) recombinant mKC (murine KC).

Information d'application

Indications d'application: ELISA: To detect mKC by direct ELISA (using 100 l/well antibody solution) this antibody can beused at a concentration of 0.15-0.30 μg/mL. Used in conjunction with compatiblesecondary reagents, allows the detection of at least 0.2 ng/well of recombinant mKC. Sandwich: To detect mKC by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with Polyclonal Anti-Murine KC (PP023P1 or PP023P2) as a captureantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mKC. Western Blot:

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2-8 °C for one month or at -20 °C for longer.

Détails sur CXCL1

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Autre désignation: CXCL1 / GRO-alpha (CXCL1 Produits)

Synonymes: anticorps FSP, anticorps GRO1, anticorps GROa, anticorps MGSA, anticorps MGSA-a, anticorps NAP-3, anticorps SCYB1, anticorps CINC-1, anticorps Gro1, anticorps CXCL1, anticorps Sdf1, anticorps Fsp, anticorps KC, anticorps Mgsa, anticorps N51, anticorps Scyb1, anticorps gro, anticorps GRO, anticorps Gro, anticorps C-X-C motif chemokine ligand 1, anticorps chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), anticorps C-X-C motif chemokine ligand 12, anticorps chemokine (C-X-C motif) ligand 1, anticorps CXCL1, anticorps Cxcl1, anticorps Cxcl12, anticorps GRO1

Sujet: The GRO gene was originally identified by subtractive hybridization studies between normal and tumorigenic Chinese hamster embryo fibroblasts. The hamster cDNA was cloned and used as a probe for cloning of the human GRO cDNA. The GROalpha gene initially cloned from T24 cells and the gene in melanoma cells encoding melanoma growth stimulating protein (MGSA) are identical. Human cells contain three closely related, but distinct GRO genes: GRO alpha, GRO beta, and GRO gamma. GRO beta and GRO gamma share 93 % and 82 % identity, respectively, with GRO alpha at the nucleotide level. GROs are members of the chemokine alpha family that is characterized by the separation with one amino acid of the first two cysteine residues, C-X-C, in the amino acid sequence. The GRO gene has been mapped to chromosome 4q21. In normal cells, human mRNA GRO expression is found in foreskin fibroblasts, synovial fibroblasts, chondrocytes and osteocytes. Additionally, GRO mRNA has been detected in mammary fibroblasts, mammary epithelial cells, endothelial cells, activated monocytes, macrophages, and neutrophils. Characterization of the GROalpha receptor indicates the presence of low and high affinity receptors on human neutrophils.Synonyms: CXCL1, GRO, GRO-alpha(1-73), GRO1, GROA, Growth-regulated alpha protein, MGSA, Melanoma growth stimulatory activity, NAP-3, Neutrophil-activating protein 3, SCYB1

ID gène: 14825

NCBI Accession: NP_032202

UniProt: P12850

Pathways: Autophagy