DCLRE1C anticorps (AA 482-495)
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- Antigène Voir toutes DCLRE1C Anticorps
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
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Épitope
- AA 482-495
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DCLRE1C est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
- Immunogène
- This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C). Genename: DCLRE1C
- Top Product
- Discover our top product DCLRE1C Anticorps primaire
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- Indications d'application
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This antibody has been tested for use in ELISA (1: 10,000-1: 20,000), Immunohistochemistry(1: 1,000) and Western blotting (1: 500-1: 2,000). Reactivity in other immunoassays isunknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.2 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
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- Antigène
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
- Autre désignation
- Artemis (DCLRE1C Produits)
- Synonymes
- anticorps artemis, anticorps A-SCID, anticorps DCLREC1C, anticorps RS-SCID, anticorps SCIDA, anticorps SNM1C, anticorps hSNM1C, anticorps Snm1l, anticorps nuclease, anticorps 9930121L06Rik, anticorps AI661365, anticorps Art, anticorps DNA cross-link repair 1C, anticorps DCLRE1C, anticorps Dclre1c
- Sujet
- Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
- ID gène
- 64421
- NCBI Accession
- NP_001029027
- UniProt
- Q96SD1
- Pathways
- Réparation de l'ADN
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