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DCLRE1C anticorps (AA 482-495)

DCLRE1C Reactivité: Humain WB, IHC (p), EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN117935
  • Antigène Voir toutes DCLRE1C Anticorps
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Épitope
    • 15
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 482-495
    Reactivité
    • 44
    • 28
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 1
    Chèvre
    Clonalité
    • 60
    Polyclonal
    Conjugué
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DCLRE1C est non-conjugé
    Application
    • 46
    • 28
    • 23
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
    Immunogène
    This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C). Genename: DCLRE1C
    Top Product
    Discover our top product DCLRE1C Anticorps primaire
  • Indications d'application
    This antibody has been tested for use in ELISA (1: 10,000-1: 20,000), Immunohistochemistry(1: 1,000) and Western blotting (1: 500-1: 2,000). Reactivity in other immunoassays isunknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.2 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
  • Antigène
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Autre désignation
    Artemis (DCLRE1C Produits)
    Synonymes
    anticorps artemis, anticorps A-SCID, anticorps DCLREC1C, anticorps RS-SCID, anticorps SCIDA, anticorps SNM1C, anticorps hSNM1C, anticorps Snm1l, anticorps nuclease, anticorps 9930121L06Rik, anticorps AI661365, anticorps Art, anticorps DNA cross-link repair 1C, anticorps DCLRE1C, anticorps Dclre1c
    Sujet
    Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
    ID gène
    64421
    NCBI Accession
    NP_001029027
    UniProt
    Q96SD1
    Pathways
    Réparation de l'ADN
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