CAND1 anticorps (C-Term)

N° du produit ABIN117945

Détail du produit anti-CAND1 anticorps

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Épitope: AA 1130-1143, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAND1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Séquence: Human CAND2 (TIP120B) (1143 aa 125.4 kDa): 1 mstaafhiss llekmtssdk dfrfmatsdl mselqkdsiq ldedserkvv kmllrlledk 61 ngevqnlavk wlgvplgafh asllhcllpq lssprlavrk ravgalghla aacstdlfve 121 ladhlldrlp gprvptspta irtliqclgs vgrqaghrlg ahldrlvplv edfcnlddde 181 lresclqafe aflrkcpkem gphvpnvtsl clqyikhdpn ynydsdedee qmetedsefs 241 eqesedeysd dddmswkvrr aaakciaali ssrpdllpdf hctlapvlir rfkereenvk --- 901 vkflisdqph pidpllksfi gefmeslqdp dlnvrratla ffnsavhnkp slvrdllddi 961 lpllyqetki rrdlirevem gpfkhtvddg ldvrkaafec mysllesclg qldiceflnh 1021 vedglkdhyd irmltfimva rlatlcpapv lqrvdrliep lratctakvk agsvkqefek 1081 qdelkrsamr avaalltipe vgkspimadf ssqirsnpel aalfesiqkd sasapstdsm 1141 els

Specificité: This antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. It reacts with human, rat and mouse CAND2/TIP120B. Cross reactivity does occur with human, rat and mouse CAND1/TIP120A. Cross reactivity with CAND2 from other sources is not known.

Purification: Delipidation and defibrination.

Immunogène: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1130-1143 of Human CAND2/TIP120B (C-terminal) coupled to KLH.

Information d'application

Indications d'application: Western blot (1: 500-1: 1,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from transfected cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins has not been tested. A 125.4 kDa bandcorresponding to human CAND2 is detected. CAND2 is specifically expressed in muscle

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 85 mg/mL (by Refractometry)

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-CAND1 (ABIN117945)

Concejero, Chen, Wang, Wang, Lin, Liu, Yang, Yong, Lin, Jawan, Huang, Cheng, Eng: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." dans: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).

Détails sur CAND1

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Autre désignation: CAND1 (CAND1 Produits)

Synonymes: anticorps TIP120, anticorps TIP120A, anticorps ATCAND1, anticorps CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1, anticorps ETA2, anticorps HEMIVENATA, anticorps HVE, anticorps T8K22.14, anticorps T8K22_14, anticorps cullin-associated and neddylation dissociated, anticorps Tip120, anticorps Tip120A, anticorps fb78a05, anticorps wu:fb78a05, anticorps zgc:55729, anticorps tip120, anticorps tip120a, anticorps cand2, anticorps 2310038O07Rik, anticorps 6330512O03Rik, anticorps AI195005, anticorps AI846556, anticorps D10Ertd516e, anticorps Tp120a, anticorps mKIAA0829, anticorps cullin associated and neddylation dissociated 1, anticorps cullin-associated and neddylation dissociated, anticorps cullin-associated and neddylation-dissociated 1, anticorps cullin-associated and neddylation-dissociated 1 L homeolog, anticorps cullin-associated NEDD8-dissociated protein 1, anticorps cullin associated and neddylation disassociated 1, anticorps CAND1, anticorps Cand1, anticorps cand1, anticorps cand1.L, anticorps LOC100159824, anticorps LOC100177977

Sujet: CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B. While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue. This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60 % identical in amino acid sequence to TIP120A.Synonyms: Cullin-associated NEDD8-dissociated protein 1, Cullin-associated and neddylation-dissociated protein 1, KIAA0829, TBP-interacting protein TIP120A, TBP-interacting protein of 120 kDa A, TIP120, TIP120A, p120 CAND1

ID gène: 55832

NCBI Accession: NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization