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SKP1 anticorps (C-Term)

SKP1 Reactivité: Humain WB, IP, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN117959
  • Antigène Voir toutes SKP1 Anticorps
    SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 152-163, C-Term
    Reactivité
    • 55
    • 41
    • 39
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 63
    • 7
    Lapin
    Clonalité
    • 53
    • 17
    Polyclonal
    Conjugué
    • 33
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SKP1 est non-conjugé
    Application
    • 49
    • 27
    • 14
    • 13
    • 11
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Séquence
    Human SKP1 (163 aa 18.5 kDa) 1 mpsiklqssd geifevdvei akqsvtiktm ledlgmddeg dddpvplpnv naailkkviq 61 wcthhkddpp ppeddenkek rtddipvwdq eflkvdqgtl felilaanyl dikglldvtc 121 ktvanmikgk tpeeirktfn ikndfteeee aqvrkenqwc eek
    Specificité
    This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human SKP1. Cross reactivity is expected against mouse SKP1 based on a high degree of sequence homology. Cross reactivity with other SKP1 proteins or SKP1 from other sources is not known.
    Purification
    Delipidation and defibrination.
    Immunogène
    Prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 152-163 of Human SKP1 (C-terminus) coupled to KLH.
    Top Product
    Discover our top product SKP1 Anticorps primaire
  • Indications d'application
    ELISA (1/2,000-1/10,000). This antibody reacts with human SKP1 by Western blot(1/500-1/1,000) and Immunoprecipitation. The antibody Immunoprecipitates in vitrotranslated protein and protein from cell lysates (using HeLa, NIH-3T3, and others). Coimmunoprecipitation of cyclin A and Cuol1 may occur. An 18.5 kDa band correspondingto human SKP1 is detected. Most cell lines expressing SKP1 can be used as a positivecontrol.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85.0 mg/mL (by Refractometry)
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 2-8 °C.
  • Wang, He, Wang, Wang, Zhai, Zhou, Zhang, Zhai, Feng, Han: "[Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.]" dans: Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology, Vol. 16, Issue 1, pp. 111-5, (2008) (PubMed).

  • Antigène
    SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
    Autre désignation
    SKP1 / OCP2 (SKP1 Produits)
    Synonymes
    anticorps EMC19, anticorps OCP-II, anticorps OCP2, anticorps SKP1A, anticorps TCEB1L, anticorps p19A, anticorps 15kDa, anticorps 2610043E24Rik, anticorps 2610206H23Rik, anticorps SKP1, anticorps Tceb1l, anticorps p19Skp1, anticorps Skp1a, anticorps skp1a, anticorps zgc:73186, anticorps ocp2, anticorps emc19, anticorps ocp-ii, anticorps tceb1l, anticorps ARABIDOPSIS SKP1 HOMOLOGUE 1, anticorps ASK1, anticorps ATSKP1, anticorps S phase kinase-associated protein 1, anticorps T4O12.17, anticorps T4O12_17, anticorps UFO INTERACTING PROTEIN 1, anticorps UIP1, anticorps ocp-2, anticorps S-phase kinase associated protein 1, anticorps S-phase kinase-associated protein 1, anticorps S-phase kinase-associated protein 1 pseudogene, anticorps S-phase kinase-associated protein 1A, anticorps S-phase kinase-associated protein 1 S homeolog, anticorps S phase kinase-associated protein 1, anticorps SKP1, anticorps skp1, anticorps LOC100340043, anticorps Skp1a, anticorps Skp1, anticorps skp1.S
    Sujet
    SKP1 is also known as S-phase kinase-associated protein 1A, Cyclin A/CDK2-associated protein p19, p19A, p19skp1, RNA polymerase II elongation factor-like protein, Organ of Corti protein 2, OCP-II protein, OCP-2, Transcription elongation factor B, and SIII. SKP1 is an essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, SKP1 serves as an adapter that links the F-box protein to CUL1. SKP1 interacts directly with CUL1 and F-box proteins, such as BTRC and SKP2, in the SCF complex. SKP1 also interacts with FBX29 and the cyclin A/CDK2 complex. SKP1 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1 and FBXW8 and is also a component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1A, APC and TBL1X.Synonyms: Cyclin A/CDK2-associated protein p19, EMC19, OCP-2, OCP-II, Organ of Corti protein 2, RNA polymerase II elongation factor-like protein, S-phase kinase-associated protein 1, SKP1A, TCEB1L, Transcription elongation factor B, p19A, p19skp1
    ID gène
    6500
    NCBI Accession
    NP_008861
    UniProt
    P63208
    Pathways
    Cycle Cellulaire, Signalisation Hedgehog, Mitotic G1-G1/S Phases
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