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CD11b anticorps (PE)

ITGAM Reactivité: Humain, Souris, Lapin FACS Hôte: Rat Monoclonal M1-70-15 PE
N° du produit ABIN118147
  • Antigène Voir toutes CD11b (ITGAM) Anticorps
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivité
    • 280
    • 179
    • 70
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    Humain, Souris, Lapin
    Hôte
    • 155
    • 114
    • 105
    • 4
    • 1
    • 1
    Rat
    Clonalité
    • 280
    • 96
    • 1
    Monoclonal
    Conjugué
    • 126
    • 37
    • 32
    • 28
    • 21
    • 11
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    • 8
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    • 6
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    • 4
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    • 3
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    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD11b est conjugé à/à la PE
    Application
    • 280
    • 88
    • 79
    • 79
    • 63
    • 44
    • 38
    • 27
    • 24
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    Flow Cytometry (FACS)
    Purification
    Affinity Chromatography on Protein G
    Immunogène
    T cell enriched splenocytes from B10 mice. Spleen cells from an immunised DA rat were fused with cells of the mouse NS1/1.Ag4.1 myeloma cell line.
    Clone
    M1-70-15
    Isotype
    IgG2b
    Top Product
    Discover our top product ITGAM Anticorps primaire
  • Indications d'application
    Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with distilled water.
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    This product is photosensitive and should be protected from light
    Stock
    4 °C
    Stockage commentaire
    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • Antigène
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Autre désignation
    CD11b (ITGAM Produits)
    Synonymes
    anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865
    Sujet
    CD11b (integrin aM subunit) is a 165 kDa type I transmembrane glycoprotein that non-covalently associates with integrin b2 subunit (CD18), expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
    ID gène
    10090
    UniProt
    P05555
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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