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ITGA6 anticorps (FITC)

ITGA6 Reactivité: Humain, Souris, Chien, Porc, Singe, Mouton FACS Hôte: Rat Monoclonal NKI-GoH3 FITC
N° du produit ABIN118232
  • Antigène Voir toutes ITGA6 Anticorps
    ITGA6 (Integrin, alpha 6 (ITGA6))
    Reactivité
    • 127
    • 61
    • 25
    • 21
    • 15
    • 12
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Chien, Porc, Singe, Mouton
    Hôte
    • 71
    • 38
    • 25
    • 2
    Rat
    Clonalité
    • 68
    • 66
    Monoclonal
    Conjugué
    • 71
    • 12
    • 11
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA6 est conjugé à/à la FITC
    Application
    • 80
    • 54
    • 51
    • 44
    • 23
    • 20
    • 15
    • 13
    • 13
    • 13
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognises CD49F (VLA-6 alpha chain). Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.
    Purification
    Affinity chromatography on Protein G
    Immunogène
    BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
    Clone
    NKI-GoH3
    Isotype
    IgG2a
    Top Product
    Discover our top product ITGA6 Anticorps primaire
  • Indications d'application
    Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ITGA6 (Integrin, alpha 6 (ITGA6))
    Autre désignation
    CD49f / ITGA6 (ITGA6 Produits)
    Synonymes
    anticorps CD49f, anticorps ITGA6B, anticorps VLA-6, anticorps 5033401O05Rik, anticorps AI115430, anticorps Cd49f, anticorps ITGA6, anticorps inta6, anticorps im:6897425, anticorps itga6, anticorps si:dkey-32o22.1, anticorps wu:fb80g02, anticorps LOC100221694, anticorps si:dkey-18j14.1, anticorps wu:fl20e08, anticorps zgc:113088, anticorps integrin subunit alpha 6, anticorps integrin alpha 6, anticorps integrin subunit alpha 6 L homeolog, anticorps integrin, alpha 6a, anticorps integrin, alpha 6b, anticorps ITGA6, anticorps Itga6, anticorps itga6.L, anticorps itga6a, anticorps itga6b
    Sujet
    CD49f is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
    ID gène
    3655
    NCBI Accession
    NP_000201
    UniProt
    P23229
    Pathways
    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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