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CD3 anticorps (PE)

CD3 Reactivité: Humain, Primate FACS Hôte: Souris Monoclonal UCHT1 PE
N° du produit ABIN118481
  • Antigène Voir toutes CD3 Anticorps
    CD3
    Reactivité
    • 222
    • 97
    • 31
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Humain, Primate
    Hôte
    • 257
    • 52
    • 14
    • 13
    • 10
    Souris
    Clonalité
    • 334
    • 8
    Monoclonal
    Conjugué
    • 98
    • 36
    • 31
    • 26
    • 24
    • 13
    • 9
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD3 est conjugé à/à la PE
    Application
    • 294
    • 93
    • 59
    • 52
    • 45
    • 45
    • 39
    • 24
    • 16
    • 10
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    • 7
    • 4
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    Flow Cytometry (FACS)
    Specificité
    This antibody recognises CD3, a 19 kDa cell surface protein which is expressed on more than 95 % of circulating peripheral blood T-cells.
    Purification
    Affinity chromatography on Protein G
    Immunogène
    Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.
    Clone
    UCHT1
    Isotype
    IgG1
    Top Product
    Discover our top product CD3 Anticorps primaire
  • Indications d'application
    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with distilled water.
    Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    This product is photosensitive and should be protected from light
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Antigène
    CD3
    Autre désignation
    CD3 (CD3 Produits)
    Synonymes
    anticorps CD3, anticorps AI504783, anticorps CD3epsilon, anticorps T3e, anticorps cd3-gamma, anticorps cd3g, anticorps cd3g-a, anticorps cd3g/d, anticorps cd3gd, anticorps t3g, anticorps CD3e molecule, anticorps CD3d molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps CD3g molecule S homeolog, anticorps CD3E, anticorps CD3D, anticorps Cd3e, anticorps cd3g.S
    Sujet
    T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    ID gène
    916
    NCBI Accession
    NP_000724
    UniProt
    P07766
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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