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ITGA2 anticorps

ITGA2 Reactivité: Humain, Singe FACS, WB, IP, IHC (p), IHC (fro), EIA Hôte: Souris Monoclonal 16B4 unconjugated
N° du produit ABIN118720
  • Antigène Voir toutes ITGA2 Anticorps
    ITGA2 (Integrin alpha 2 (ITGA2))
    Reactivité
    • 129
    • 73
    • 21
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Singe
    Hôte
    • 82
    • 46
    • 30
    • 7
    • 7
    Souris
    Clonalité
    • 100
    • 75
    Monoclonal
    Conjugué
    • 70
    • 24
    • 19
    • 16
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA2 est non-conjugé
    Application
    • 82
    • 66
    • 44
    • 42
    • 18
    • 17
    • 15
    • 12
    • 11
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labelled cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein G
    Immunogène
    Purified human beta1 preparation from HT1080 fibrosarcoma cell extract. Spleen cells from immunised BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line.
    Clone
    16B4
    Isotype
    IgG1
    Top Product
    Discover our top product ITGA2 Anticorps primaire
  • Indications d'application
    Flow Cytometry: 30 μg/mL, Immunoprecipitation: 25-50 μg/mL. Immunohistochemistry on Frozen Sections: 30-40 μg/mL. ELISA: 10 μg/mL. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ITGA2 (Integrin alpha 2 (ITGA2))
    Autre désignation
    CD49b / ITGA2 (ITGA2 Produits)
    Synonymes
    anticorps BR, anticorps CD49B, anticorps GPIa, anticorps HPA-5, anticorps VLA-2, anticorps VLAA2, anticorps DX5, anticorps integrin subunit alpha 2, anticorps integrin alpha 2, anticorps ITGA2, anticorps Itga2
    Sujet
    CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha-2 chain. CD49b associates noncovalently with CD29, the integrin beta-1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg++ dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
    ID gène
    3673
    NCBI Accession
    NP_002194
    UniProt
    P17301
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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