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CD79a anticorps (FITC)

CD79A Reactivité: Humain FACS Hôte: Souris Monoclonal ZL7-4 FITC
N° du produit ABIN118795
  • Antigène Voir toutes CD79a (CD79A) Anticorps
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Reactivité
    • 192
    • 102
    • 81
    • 52
    • 51
    • 32
    • 28
    • 26
    • 26
    • 26
    • 16
    • 10
    • 5
    • 5
    • 2
    • 1
    Humain
    Hôte
    • 105
    • 101
    • 3
    • 1
    Souris
    Clonalité
    • 127
    • 82
    • 1
    Monoclonal
    Conjugué
    • 93
    • 19
    • 16
    • 15
    • 15
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD79a est conjugé à/à la FITC
    Application
    • 119
    • 97
    • 64
    • 58
    • 46
    • 25
    • 22
    • 15
    • 10
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody reacts with CD79a positive cells by flow cytometry. This clone has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays.
    Immunogène
    IgM complex isolated from Daudi cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
    Clone
    ZL7-4
    Isotype
    IgG1
    Top Product
    Discover our top product CD79A Anticorps primaire
  • Indications d'application
    Flow Cytometry: Use 10 μL of neat antibody to label 1x10^6 cells in 100 μL. We recommend incubation times of at least 30 minutes with this antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Autre désignation
    CD79a (CD79A Produits)
    Synonymes
    anticorps CD79A, anticorps Ig-alpha, anticorps Iga, anticorps Igalpha, anticorps Ly-54, anticorps Ly54, anticorps mb-1, anticorps IGA, anticorps MB-1, anticorps IG-alpha, anticorps CD79a molecule, anticorps CD79A antigen (immunoglobulin-associated alpha), anticorps Cd79a molecule-like, anticorps CD79A, anticorps Cd79a, anticorps Cd79al
    Sujet
    A disulfide-linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non-covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
    ID gène
    973
    NCBI Accession
    NP_001774
    UniProt
    P11912
    Pathways
    BCR Signaling
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