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HLAG anticorps

HLAG Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal MEM-G-1 unconjugated
N° du produit ABIN119228
  • Antigène Voir toutes HLAG Anticorps
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Reactivité
    • 125
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 66
    • 65
    • 3
    • 1
    • 1
    Souris
    Clonalité
    • 69
    • 67
    Monoclonal
    Conjugué
    • 52
    • 20
    • 19
    • 15
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLAG est non-conjugé
    Application
    • 86
    • 69
    • 59
    • 43
    • 30
    • 27
    • 15
    • 13
    • 13
    • 11
    • 10
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    The antibody reacts with denaturated HLA-G heavy chain. HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.
    Purification
    Affinity Chromatography on Protein-A
    Immunogène
    Recombinant Human HLA-G denaturated heavy chain
    Clone
    MEM-G-1
    Isotype
    IgG1
    Top Product
    Discover our top product HLAG Anticorps primaire
  • Indications d'application
    Western Blotting. Immunohistochemistry (paraffin sections): 1:60 to 1:100, 1 h at RT. Positive tissue: Human placenta - extravillous cytotrophoblast. Staining technique: Standard ABC technique. Pretreatment: Heat retrieval in 0.01 M citrate buffer (4x2 min. in microwave oven).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to - 70 °C for longer.
  • Antigène
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Autre désignation
    HLA Class I alpha G / HLA-G (HLAG Produits)
    Synonymes
    anticorps MHC-G, anticorps B-F, anticorps B-F-S04, anticorps B-F-S05, anticorps B-F-S06, anticorps B-F-S07, anticorps B-FI, anticorps B-FIV, anticorps BF2, anticorps BFa2, anticorps BFw-03, anticorps BFw-05, anticorps BFz-01, anticorps major histocompatibility complex, class I, G, anticorps MHC BF1 class I, anticorps HLA-G, anticorps BF1
    Sujet
    HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of a heavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternate splicing provides both soluble and membrane bound forms of HLA G, with two soluble isoforms and four membrane bound isoforms. HLA G may be part of the fetal protection system and is expressed on fetal derived placental cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G
    ID gène
    3135
    NCBI Accession
    NP_002118
    UniProt
    P17693
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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