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CD226 anticorps (FITC)

CD226 Reactivité: Humain FACS Hôte: Souris Monoclonal DX11 FITC
N° du produit ABIN119796
  • Antigène Voir toutes CD226 Anticorps
    CD226
    Reactivité
    • 74
    • 20
    • 5
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 23
    • 8
    Souris
    Clonalité
    • 49
    • 35
    • 1
    Monoclonal
    Conjugué
    • 46
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD226 est conjugé à/à la FITC
    Application
    • 45
    • 32
    • 32
    • 16
    • 14
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. We recommend the use of SM2023A for funtional studies.
    Purification
    Affinity chromatography on Protein G
    Immunogène
    Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
    Clone
    DX11
    Isotype
    IgG1
    Top Product
    Discover our top product CD226 Anticorps primaire
  • Indications d'application
    Flow Cytometry: 1/10 - 1/20, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1.0 % Bovine Serum Albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD226
    Autre désignation
    CD226 / DNAM1 (CD226 Produits)
    Synonymes
    anticorps CD226, anticorps cd226, anticorps zgc:158817, anticorps BC051526, anticorps DNAM-1, anticorps DNAM1, anticorps Pta1, anticorps TLiSA1, anticorps PTA1, anticorps CD226 molecule, anticorps CD226 antigen, anticorps CD226, anticorps cd226, anticorps Cd226
    Sujet
    CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Synonyms: DNAM-1, DNAX accessory molecule 1
    ID gène
    10666
    NCBI Accession
    NP_006557
    UniProt
    Q15762
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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