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CD226 anticorps

CD226 Reactivité: Humain FACS, IP, Func Hôte: Souris Monoclonal DX11 unconjugated
N° du produit ABIN119797
  • Antigène Voir toutes CD226 Anticorps
    CD226
    Reactivité
    • 74
    • 20
    • 5
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 23
    • 8
    Souris
    Clonalité
    • 49
    • 35
    • 1
    Monoclonal
    Conjugué
    • 46
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD226 est non-conjugé
    Application
    • 45
    • 32
    • 32
    • 16
    • 14
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    Specificité
    This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells
    Purification
    Affinity chromatography on Protein G
    niveau d'endotoxine
    Low Endotoxin
    Immunogène
    Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line.
    Clone
    DX11
    Isotype
    IgG1
    Top Product
    Discover our top product CD226 Anticorps primaire
  • Indications d'application
    Flow Cytometry: 1/50 - 1/200, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. Should this product contain a precipitate, we recommend centrifugation before use.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
  • Antigène
    CD226
    Autre désignation
    CD226 / DNAM1 (CD226 Produits)
    Synonymes
    anticorps CD226, anticorps cd226, anticorps zgc:158817, anticorps BC051526, anticorps DNAM-1, anticorps DNAM1, anticorps Pta1, anticorps TLiSA1, anticorps PTA1, anticorps CD226 molecule, anticorps CD226 antigen, anticorps CD226, anticorps cd226, anticorps Cd226
    Sujet
    CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes.Synonyms: DNAM-1, DNAX accessory molecule 1
    ID gène
    10666
    NCBI Accession
    NP_006557
    UniProt
    Q15762
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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