NCR1 anticorps (PE)

N° du produit ABIN120215

Détail du produit anti-NCR1 anticorps (PE)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivité: Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCR1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.

Purification: Affinity Chromatography on Protein G.

Immunogène: Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.

Clone: AKS1

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: neat- 1/5, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized and reconstituted antibody ist stable at 2 - 8 °C for up to one month or at -20 °C for longer.

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: CD335 / NKp46 (NCR1 Produits)

Synonymes: anticorps CD335, anticorps LY94, anticorps NK-p46, anticorps NKP46, anticorps Ly94, anticorps NKp46, anticorps KILR-1, anticorps Nk-p46, anticorps Nkp46, anticorps natural cytotoxicity triggering receptor 1, anticorps NCR1, anticorps Ncr1

Sujet: CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei

ID gène: 369024

NCBI Accession: NP_899209

UniProt: Q863H2

Pathways: Regulation of Leukocyte Mediated Immunity