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HLA-E anticorps

HLA-E Reactivité: Humain, Primate FACS, IP, IHC (p) Hôte: Souris Monoclonal MEM-E-06 unconjugated
N° du produit ABIN120711
  • Antigène Voir toutes HLA-E Anticorps
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Reactivité
    • 71
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Primate
    Hôte
    • 44
    • 28
    Souris
    Clonalité
    • 46
    • 26
    Monoclonal
    Conjugué
    • 31
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-E est non-conjugé
    Application
    • 43
    • 29
    • 20
    • 13
    • 13
    • 12
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    The antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
    Purification
    Protein-A affinity chromatography
    Pureté
    > 95 % pure (by SDS-PAGE)
    Immunogène
    Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide
    Clone
    MEM-E-06
    Isotype
    IgG1
    Top Product
    Discover our top product HLA-E Anticorps primaire
  • Indications d'application
    Flow Cytometry. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Abstract
    HLA-E Produits
    Synonymes
    anticorps EA1.2, anticorps EA2.1, anticorps HLA-6.2, anticorps MHC, anticorps QA1, anticorps major histocompatibility complex, class I, E, anticorps HLA-E, anticorps PATR-E
    Sujet
    HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.2, HLAE, MHC class I antigen E, alpha chain E
    ID gène
    3133
    UniProt
    P13747
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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