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Détail du produit
anti-NF-kB p65 / RELA anticorps
Aperçu
| Antigène: | NF-kB p65 / RELA |
| Clonalité: | Polyclonal |
| Application: | Transfer Western (WB) |
| Reactivité: | Humain, Souris |
| Hôte: | Lapin |
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1 référence disponible |
| Quantité: | |
| Prix: | 280,00 € (Plus frais de livraison et TVA) |
| Numéro du produit: | ABIN123408 |
| Disponibilité: | Envoi sous 7 à 10 jours ouvrables |
Description du produit » anti-NF-kB p65 / RELA anticorps
| Antigène | NF-kB p65 / RELA |
| Swiss-Prot | Q04206 |
| Immunogène | Synthetic peptide corresponding to aa 538-546 of human p65 |
| Reactivité | Humain, Souris |
| Hôte | Lapin |
| Clonalité | Polyclonal |
| Format | Purified |
| Description | NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65. |
| Specificité | The antibody reacts with Nuclear Factor kB. |
Applications » anti-NF-kB p65 / RELA anticorps
| Application | Transfer Western (WB) |
| Indications d'application | Western blot analysis: 1:500-1:1000. Recommended positive control: HeLa or RAW cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Buffer | PBS containing 0.02% sodium azide and 0.1 mg/ml BSA |
| Stock | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch. |
| Restrictions | For Research Use only |
Références » anti-NF-kB p65 / RELA anticorps
| Références |
Ganchi, Sun, Greene et al.: "I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding." In: Molecular biology of the cell, Vol. 3, Issue 12, pp. 1339-52, 1993 (PubMed)
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Images » anti-NF-kB p65 / RELA anticorps
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