anti-matrix metalloprotease 1 (MMP1) anticorps

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	Antigène:	Matrix metalloprotease 1 (MMP1)
	Clonalité:	Polyclonal
	Application:	Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
	Reactivité:	Human
	Hôte:	Rabbit
	Quantité:	500µl (100ug/ml approximately) (Alternatives)
	Prix:	278,00 $ (Plus frais de livraison $25 et TVA, Invoice in EUR)
	Numéro du produit:	ABIN125608
	Disponibilité:	Envoi sous 5 jours ouvrables

Antigène	Matrix metalloprotease 1 (MMP1)
Immunogène	A synthetic peptide from the middle region of the human MMP-1.
Reactivité	Human
Clonalité	Polyclonal
Format	Ig Fraction, Purified
Hôte	Rabbit
Specificité	This antibody reacts with a 52 kD protein (unglycosylated) and 57 kD (glycosylated) species of pro form of MMP-1 as well as 42 kD (unglycosylated) and 47 kD (glycosylated) active form of MMP-1. Matrix metalloproteinase (MMPs) are a family of closely related zinc-containing proteolytic enzymes, capable of degrading connective tissue components. MMP-1 appears to be associated with facilitating the tumor spread and invasion of esophageal and colorectal cancers and is associated with poor prognosis. Interstitial collagenase (MMP-1), 73 kD gelatinase A/type IV collagenase (MMP-2) and 92 kD gelatinase B/type IV collagenase (MMP-9) dissolve extracellular matrix and may initiate and promote angiogenesis.

Application	Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Indications d'application	Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Placenta. Cellular localization: Cytoplasmic
Concentration	100ug/ml approximately
Buffer	Purified immunoglobulin fraction of rabbit antiserum against MMP-1 containing sodium azide as preservative.
Stock	Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Domaine de recherche	Extracellular Matrix
Restrictions	For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union