Cytokeratin 18 anticorps
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- Antigène Voir toutes Cytokeratin 18 (KRT18) Anticorps
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Reactivité
- Humain, Boeuf (Vache)
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cytokeratin 18 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificité
- Ks 18.27 represents an excellent marker to discriminate simple epithelia from those of different origin. Polypeptide reacting: Mr 45,000 polypeptide (keratin K18, formerly also designated cytokeratin 18) of all simple type and complex epithelia. Reacts with human, bovine, negative with mouse. Reacts with MCF-7, HeLa. A-431, PLC, RT 112. All adeno-CA tested, undifferentiated CA, cervix CA, hepatocellular CA.
- Purification
- Protein A affinity chromatography
- Immunogène
- Cytoskeletal preparation from tumor cell line MCF-7.
- Clone
- Ks18-27
- Isotype
- IgG1
- Top Product
- Discover our top product KRT18 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on frozen sections: 1: 10, 1 h at RT. Cytological material. Immunoblotting. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in 1 mL dist. water
- Buffer
- PBS buffer, pH 7.4 containing 0.09 % sodium azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- This product is photosensitive and should be protected from light
- Stock
- 4 °C
- Stockage commentaire
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Antigène
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Autre désignation
- Cytokeratin 18 (KRT18 Produits)
- Synonymes
- anticorps CK18, anticorps K18, anticorps Krt1-18, anticorps CYK18, anticorps DreK18, anticorps cb83, anticorps dapk1, anticorps sb:cb83, anticorps wu:fa13f02, anticorps wu:fb36b04, anticorps krt18, anticorps MGC64569, anticorps MGC75922, anticorps KRT18, anticorps CK-18-A, anticorps K18-A, anticorps NC-11, anticorps cyk18, anticorps k18, anticorps krt18-a, anticorps krt18-b, anticorps krt18a, anticorps xkendob, anticorps keratin 18, anticorps keratin 18, type I L homeolog, anticorps keratin 18, type I, anticorps keratin, type I cytoskeletal 18, anticorps K18, simple type I keratin, anticorps Keratin, type I cytoskeletal 18, anticorps keratin 18, type I S homeolog, anticorps Krt18, anticorps KRT18, anticorps krt18, anticorps krt18.L, anticorps LOC700569, anticorps LOC100136778, anticorps k1c18, anticorps LOC100008885, anticorps krt18.S
- Sujet
- Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
- ID gène
- 3875
- NCBI Accession
- NP_000215
- UniProt
- P05783
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
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