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Synaptophysin anticorps

SYP Reactivité: Humain, Souris, Rat, Boeuf (Vache) WB, IF, IHC (p), IHC (fro) Hôte: Souris Monoclonal SY38 unconjugated
N° du produit ABIN126707
  • Antigène Voir toutes Synaptophysin (SYP) Anticorps
    Synaptophysin (SYP)
    Reactivité
    • 75
    • 55
    • 54
    • 10
    • 9
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache)
    Hôte
    • 54
    • 34
    • 3
    • 1
    Souris
    Clonalité
    • 51
    • 41
    Monoclonal
    Conjugué
    • 70
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Synaptophysin est non-conjugé
    Application
    • 70
    • 42
    • 29
    • 20
    • 20
    • 15
    • 15
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    SY38 represents an excellent Marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin: Pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid. Polypeptide Reacting: Mr 38 000 transmembrane glycoprotein of presynaptic vesicles. Reactivity on Cultured Cell Lines: Rat PC-12 cell line.
    Purification
    Affinity Chromatography on Protein A.
    Immunogène
    Synaptophysin from presynaptic vesicles, prepared from bovine brain.
    Clone
    SY38
    Isotype
    IgG1
    Top Product
    Discover our top product SYP Anticorps primaire
  • Indications d'application
    Immunoblotting. Immunofluorescence. Cytological Material. Immunohistochemistry on Frozen and Paraffin Sections: 1/50 with PBS, pH 7.4. In no case Protease Pretreatment. Incubation Time: 1 h at RT, extended with Paraffin.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in 1 mL distilled water.
    Buffer
    Final Solution contains PBS, pH 7.4 with 0.09 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody (in aliquots) at -20 °C.
  • Antigène
    Synaptophysin (SYP)
    Autre désignation
    Synaptophysin / SYP (SYP Produits)
    Synonymes
    anticorps syp-B, anticorps xsypii, anticorps MGC86267, anticorps MRXSYP, anticorps A230093K24Rik, anticorps AI848995, anticorps Syn, anticorps p38, anticorps Syp1, anticorps mrxsyp, anticorps syp, anticorps xsypi, anticorps synaptophysin S homeolog, anticorps synaptophysin, anticorps synaptophysin L homeolog, anticorps synaptophysin a, anticorps syp.S, anticorps SYP, anticorps syp, anticorps Syp, anticorps syp.L, anticorps sypa
    Sujet
    Synaptophysin is a glycoprotein present in the membrane of neuronal presynaptic vesicles in brain, spinal cord, retina, vesicles of adrenal medulla, neuromuscular junctions, and endocrine cells. It is also expressed by neuroendocrine cells throughout the body, both normal and neoplastic. Synaptophysin is a useful marker for the identification of normal neuroendocrine cells and neuroendocrine neoplasms. This antibody reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, and gastointestinal mucosa. It also reacts with a wide spectrum of neuroendocrine neoplasms of neural type including neuroblastomas, ganglioneuroblastomas, ganglioneuromas, pheochromocytomas, chromaffin, and non chromaffin paragangliomas.Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker
    ID gène
    6855
    NCBI Accession
    NP_003170
    UniProt
    P08247
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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