LRP5 anticorps (Low Density Lipoprotein Receptor-Related Protein 5)

Details for Product anti-LRP5 Antibody No. ABIN127323, Fournisseur: Connectez-vous pour afficher
Antigène
  • Xlrp5
  • bmnd1
  • evr1
  • evr4
  • hbm
  • lr3
  • lrp5-A
  • lrp7
  • oppg
  • ops
  • opta1
  • vbch2
  • LRP5
  • LRP6
  • BMND1
  • EVR1
  • EVR4
  • HBM
  • LR3
  • LRP7
  • OPPG
  • OPS
  • OPTA1
  • VBCH2
  • mKIAA4142
  • low density lipoprotein receptor-related protein 5
  • LRP5
  • lrp5
  • LOC100220027
  • Lrp5
Alternatives
anti-Humain LRP5 anticorps pour Immunofluorescence (fixed cells)
Reactivité
Humain, Souris
105
81
49
3
2
1
1
1
1
Hôte
Lapin
97
16
12
2
Clonalité
Polyclonal
Conjugué
Cet anticorp LRP5 est non-conjugé
8
8
7
5
5
5
3
3
3
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
81
61
36
29
14
7
5
4
2
2
2
1
Options
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Immunogène Synthetic peptide surrounding amino acid 437 of Human LRP.
Isotype IgG
Réactivité croisée (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity Chromatography
Autre désignation LRP5 + LRP6 (LRP5 Antibody Extrait)
Sujet LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Want signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and beta-catenin stabilization.Synonyms: LRP5, LRP6, LRP7, Low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 6
Domaine de recherche Stem Cells, Wnt, Extracellular Matrix, Wnt Signaling
Pathways Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
Indications d'application Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative
Agent conservateur Thimerosal (Merthiolate)
Précaution d'utilisation This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock -20 °C/-80 °C
Stockage commentaire Store the antibody undiluted at -20 °C or at -70 °C (in aliquots) for long term storage.
Supplier Images
 image for anti-LRP5 anticorps (Low Density Lipoprotein Receptor-Related Protein 5) (ABIN127323) anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibody
Produit citée dans: Del Valle-Pérez, Arqués, Vinyoles, de Herreros, Duñach: "Coordinated action of CK1 isoforms in canonical Wnt signaling." dans: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2877-88, 2011 (PubMed).

Casagolda, Del Valle-Pérez, Valls, Lugilde, Vinyoles, Casado-Vela, Solanas, Batlle, Reynolds, Casal, de Herreros, Duñach: "A p120-catenin-CK1epsilon complex regulates Wnt signaling." dans: Journal of cell science, Vol. 123, Issue Pt 15, pp. 2621-31, 2010 (PubMed).