ING5 anticorps (AA 127-140)

N° du produit ABIN129552

Détail du produit anti-ING5 anticorps

Antigène: ING5 (Inhibitor of Growth Family, Member 5 (ING5))

Épitope: AA 127-140

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ING5 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 127-140 of Human p28 ING5protein (Inhibitor of growth family, member 5). This sequence shows homology to and 2 for ING5.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 28 kDa or 26 kDa in size corresponding to variants of ING5 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.52 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-ING5 (ABIN129552)

Iizuka, Sarmento, Sekiya, Scrable, Allis, Smith: "Hbo1 Links p53-dependent stress signaling to DNA replication licensing." dans: Molecular and cellular biology, Vol. 28, Issue 1, pp. 140-53, (2007) (PubMed).

Détails sur ING5

Antigène: ING5 (Inhibitor of Growth Family, Member 5 (ING5))

Autre désignation: p28 ING5 (ING5 Produits)

Synonymes: anticorps p28ING5, anticorps 1700001C14Rik, anticorps 1700027H23Rik, anticorps 1810018M11Rik, anticorps AI225768, anticorps p28ing5, anticorps MGC76007, anticorps ING5, anticorps MGC133862, anticorps ING1, anticorps p33, anticorps si:busm1-40g1.1, anticorps si:dz40g1.1, anticorps wu:fc94a02, anticorps zgc:100910, anticorps ing5, anticorps inhibitor of growth family member 5, anticorps inhibitor of growth family, member 5, anticorps inhibitor of growth family member 5 L homeolog, anticorps inhibitor of growth family, member 5b, anticorps inhibitor of growth family, member 5a, anticorps ING5, anticorps Ing5, anticorps ing5, anticorps ing5.L, anticorps ing5b, anticorps ing5a

Sujet: P28 ING5 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.  Multiple alternatively spliced transcript variants have been observed.  The accession number listed below is for variant (1) encodes the longest isoform.
Synonyms: ING5 antibody, Inhibitor of growth family member 5 antibody

ID gène: 84289, 18644730

UniProt: Q8WYH8

Pathways: Chromatin Binding