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CD72.1 anticorps

Reactivité: Souris FACS Hôte: Souris Monoclonal 10-1-D2 unconjugated
N° du produit ABIN135264
  • Antigène Tous les produits CD72.1
    CD72.1
    Reactivité
    Souris
    Hôte
    • 7
    Souris
    Clonalité
    • 7
    Monoclonal
    Conjugué
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CD72.1 est non-conjugé
    Application
    Flow Cytometry (FACS)
    Specificité
    Mouse CD72.1, Mr 45 kDa
    Attributs du produit
    Mouse Anti-Mouse CD72.1-UNLB
    Purification
    Purified
    Immunogène
    DBA/2 mouse spleen cells
    Clone
    10-1-D2
    Isotype
    IgG2b
  • Indications d'application
    • Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature , Block - Reported in literature , Costim - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells APC and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro blocking and proliferation assays

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Antigène
    CD72.1
    Abstract
    CD72.1 Produits
    Sujet
    CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing.
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