TNFRSF10B anticorps

N° du produit ABIN1383914

Détail du produit anti-TNFRSF10B anticorps

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF10B est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: Recognises a 42-46 kDa protein

Purification: Ion exchange chromatography

Immunogène: Recombinant human TRAIL R2/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-K29

Isotype: IgG1 kappa

Information d'application

Indications d'application: Use 10 μL to label 10^6 cells or 100 μL of whole blood

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate-buffered saline with 1 % BSA and 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Références pour anticorps anti-TNFRSF10B (ABIN1383914)

Ueda, Kohanbash, Sasaki, Fujita, Zhu, Kastenhuber, McDonald, Potter, Hamilton, Lotze, Khan, Sobol, Okada: "Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10746-51, (2009) (PubMed).

Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: "Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2." dans: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7046-55, (2006) (PubMed).

Détails sur TNFRSF10B

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Autre désignation: TRAIL R2 (TNFRSF10B Produits)

Synonymes: anticorps TNFRSF10B, anticorps dr5, anticorps cd262, anticorps killer, anticorps trick2, anticorps trickb, anticorps xDR-M1, anticorps xDR-M2, anticorps ztnfr9, anticorps trailr2, anticorps trick2a, anticorps trick2b, anticorps CD262, anticorps DR5, anticorps KILLER, anticorps KILLER/DR5, anticorps TRAIL-R2, anticorps TRAILR2, anticorps TRICK2, anticorps TRICK2A, anticorps TRICK2B, anticorps TRICKB, anticorps ZTNFR9, anticorps Ly98, anticorps MK, anticorps tumor necrosis factor receptor superfamily, member 10b, anticorps tumor necrosis factor receptor superfamily member 10b S homeolog, anticorps tumor necrosis factor receptor superfamily member 10b L homeolog, anticorps tumor necrosis factor receptor superfamily member 10b, anticorps TNF receptor superfamily member 10b, anticorps Tnfrsf10b, anticorps TNFRSF10B, anticorps tnfrsf10b.S, anticorps tnfrsf10b.L, anticorps tnfrsf10b

Sujet: DR5, TRAIL R2

Poids moléculaire: 42-46 kDa

Pathways: Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity