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TNF alpha anticorps

TNF alpha Reactivité: Humain ELISA, IHC, Func, ELISpot Hôte: Souris Monoclonal B-C7 unconjugated
N° du produit ABIN1383955
  • Antigène Voir toutes TNF alpha Anticorps
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Reactivité
    • 333
    • 203
    • 129
    • 67
    • 51
    • 42
    • 27
    • 26
    • 23
    • 16
    • 12
    • 10
    • 10
    • 9
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 262
    • 203
    • 46
    • 26
    • 6
    • 3
    • 2
    • 2
    • 2
    Souris
    Clonalité
    • 279
    • 264
    Monoclonal
    Conjugué
    • 260
    • 89
    • 45
    • 20
    • 19
    • 13
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNF alpha est non-conjugé
    Application
    • 355
    • 217
    • 140
    • 130
    • 74
    • 64
    • 58
    • 54
    • 49
    • 42
    • 40
    • 37
    • 37
    • 32
    • 20
    • 11
    • 10
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Functional Studies (Func), ELISpot
    Specificité
    Recognises both natural and recombinant human TNF-a
    Purification
    Ion exchange chromatography
    Stérilité
    0.22 μm filtered
    Immunogène
    Recombinant human TNF-a,Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-C7
    Isotype
    IgG1 kappa
    Biological Activity Comment
    Inhibits TNFα induced cytotoxicity on U937 cells
    Top Product
    Discover our top product TNF alpha Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    Agent conservateur
    Without preservative
    Stock
    4 °C
    Stockage commentaire
    Store at +2-8°C for 12 months. DO NOT FREEZE.
  • Arduise, Abache, Li, Billard, Chabanon, Ludwig, Mauduit, Boucheix, Rubinstein, Le Naour: "Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 10, pp. 7002-13, (2008) (PubMed).

    Venet, Pachot, Debard, Bohe, Bienvenu, Lepape, Powell, Monneret: "Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 9, pp. 6540-7, (2006) (PubMed).

    Dyugovskaya, Lavie, Lavie: "Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea." dans: American journal of respiratory and critical care medicine, Vol. 168, Issue 2, pp. 242-9, (2003) (PubMed).

    Limb, Daniels, Pleass, Charteris, Luthert, Khaw: "Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha." dans: The American journal of pathology, Vol. 160, Issue 5, pp. 1847-55, (2002) (PubMed).

    Hamacher, Lucas, Lijnen, Buschke, Dunant, Wendel, Grau, Suter, Ricou: "Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome." dans: American journal of respiratory and critical care medicine, Vol. 166, Issue 5, pp. 651-6, (2002) (PubMed).

    Musey, Ding, Cao, Lee, Galloway, Yuen, Jerome, McElrath: "Ontogeny and specificities of mucosal and blood human immunodeficiency virus type 1-specific CD8(+) cytotoxic T lymphocytes." dans: Journal of virology, Vol. 77, Issue 1, pp. 291-300, (2002) (PubMed).

    Marfaing-Koka, Maravic, Humbert, Galanaud, Emilie: "Contrasting effects of IL-4, IL-10 and corticosteroids on RANTES production by human monocytes." dans: International immunology, Vol. 8, Issue 10, pp. 1587-94, (1997) (PubMed).

    Voorzanger, Touitou, Garcia, Delecluse, Rousset, Joab, Favrot, Blay: "Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors." dans: Cancer research, Vol. 56, Issue 23, pp. 5499-505, (1997) (PubMed).

    Mey, Hmama, Normier, Revillard: "Alteration of dealcylated lipopolysaccharide antagonistic properties by interaction with plasma factors." dans: Journal of leukocyte biology, Vol. 61, Issue 1, pp. 17-23, (1997) (PubMed).

    Ida, Robertson, Voss, Ritz, Anderson: "CD94 ligation induces apoptosis in a subset of IL-2-stimulated NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2154-60, (1997) (PubMed).

    van Hensbroek, Palmer, Onyiorah, Schneider, Jaffar, Dolan, Memming, Frenkel, Enwere, Bennett, Kwiatkowski, Greenwood: "The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria." dans: The Journal of infectious diseases, Vol. 174, Issue 5, pp. 1091-7, (1996) (PubMed).

    Racadot, Milpied, Bordigoni, Cahn, Plouvier, Lioure, Lutz, Wijdenes, Herve: "Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients." dans: Bone marrow transplantation, Vol. 15, Issue 5, pp. 669-77, (1995) (PubMed).

    Boillot, Capellier, Racadot, Wijdenes, Herve, Barale: "Pilot clinical trial of an anti-TNF alpha monoclonal antibody for the treatment of septic shock." dans: Clinical intensive care : international journal of critical & coronary care medicine, Vol. 6, Issue 2, pp. 52-6, (1995) (PubMed).

    Hervé, Flesch, Tiberghien, Wijdenes, Racadot, Bordigoni, Plouvier, Stephan, Bourdeau, Holler: "Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease." dans: Blood, Vol. 79, Issue 12, pp. 3362-8, (1992) (PubMed).

    Hervé, Racadot, Wijdenes, Flesch, Tiberghien, Bordigoni, Holler, Powles, Bourdeau, Wilmer: "Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody." dans: Bone marrow transplantation, Vol. 7 Suppl 2, pp. 149, (1991) (PubMed).

  • Antigène
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Autre désignation
    TNF alpha (TNF alpha Produits)
    Synonymes
    anticorps DIF, anticorps TNF-alpha, anticorps TNFA, anticorps TNFSF2, anticorps RATTNF, anticorps Tnfa, anticorps tnf, anticorps TNF-a, anticorps TNFalpha, anticorps Tnfsf1a, anticorps TNFa, anticorps cTNF, anticorps Tnf-alpha, anticorps tnfa-like, anticorps TNF-ALPHA, anticorps dif, anticorps tnfa, anticorps xtnf, anticorps tnfsf2, anticorps tnf-alpha, anticorps Cachectin, anticorps tumor necrosis factor, anticorps tumor necrosis factor b (TNF superfamily, member 2), anticorps tumor necrosis factor alpha, anticorps tumor necrosis factor a (TNF superfamily, member 2), anticorps TNF, anticorps Tnf, anticorps tnf, anticorps tnfb, anticorps tnf-alpha, anticorps LOC103694380, anticorps tnfa
    Sujet
    TNFa
    Pathways
    Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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