EHMT2 anticorps (C-Term)

N° du produit ABIN1449182

Détail du produit anti-EHMT2 anticorps

Antigène: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Épitope: AA 621-1000, C-Term

Reactivité: Humain, Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp EHMT2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts with both the 165 kDa G9a-L isoform and the 140 kDa G9a-S isoform.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Protein A agarose

Immunogène: GST-mouse G9a C-terminal protein (a.a. 621-1000)

Clone: 01-01-14

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EHMT2

Antigène: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Autre désignation: BAT8 (EHMT2 Produits)

Synonymes: anticorps BAT8, anticorps C6orf30, anticorps G9A, anticorps GAT8, anticorps KMT1C, anticorps NG36, anticorps T27C4.12, anticorps T27C4_12, anticorps DL3235W, anticorps FCAALL.188, anticorps T18B16.120, anticorps T18B16_120, anticorps F9H3.13, anticorps F9H3_13, anticorps F9H3.7, anticorps F9H3_7, anticorps F9H3.9, anticorps F9H3_9, anticorps F9H3.6, anticorps F9H3_6, anticorps F13G24.40, anticorps T20K14.110, anticorps T20K14_110, anticorps MWD22.10, anticorps MWD22_10, anticorps MRB17.12, anticorps MRB17_12, anticorps MAF19.22, anticorps MAF19_22, anticorps Bat8, anticorps D17Ertd710e, anticorps G9a, anticorps Ng36, anticorps euchromatic histone lysine methyltransferase 2, anticorps ankyrin repeat-containing protein, anticorps Ankyrin repeat family protein, anticorps euchromatic histone lysine N-methyltransferase 2, anticorps EHMT2, anticorps ank1, anticorps IscW_ISCW006888, anticorps Arnit_2917, anticorps AT3G04470, anticorps AT4G14390, anticorps AT4G19150, anticorps AT4G03500, anticorps AT4G03450, anticorps AT4G03460, anticorps AT4G03440, anticorps PIA1, anticorps AT5G15500, anticorps AT5G51160, anticorps AT5G54620, anticorps ANK6, anticorps AT1G04780, anticorps AT1G62050, anticorps Ehmt2

Sujet: G9a (BAT8, NG36) is a major histone methyltransferase that acts by adding a methyl group to the Lys9 amino acid on histone H3 proteins. Methylation of Lys9 on histone H3 is important for the regulation of the expression of crucial genes during embryogenesis. Methylation of Lys9 may also play a role in tumorigenesis, since deregulation of histone H3 Lys9 methylation in G9a-deficient cells induces the expression of Mage-2a, a tumor-specific protein whose function is unknown. The 165 kDa G9a protein has an unusual structure, containing 24 contiguous glutamate residues in the N-terminus and 6 contiguous copies of a 33-amino acid ankyrin repeat in the C-terminus. The presence of the ankyrin repeats suggest that G9a may be involved in intracellular protein-protein interactions. G9a is expressed in monocytic, macrophage, hepatocyte, T-cell, B-cell, epithelial, and promyelocytic cell lines.Synonyms: C6orf30, EHMT2, Euchromatic histone-lysine N-methyltransferase 2, H3 lysine-9 specific 3, H3-K9-HMTase 3, HLA-B-associated transcript 8, Histone H3-K9 methyltransferase 3, Histone-lysine N-methyltransferase, KMT1C, Lysine N-methyltransferase 1C, NG36, Protein G9A

ID gène: 110147

NCBI Accession: NP_665829

UniProt: Q9Z148