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MAP1LC3A anticorps

MAP1LC3A Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449593
  • Antigène Voir toutes MAP1LC3A Anticorps
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Reactivité
    • 213
    • 106
    • 87
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 175
    • 44
    • 2
    Lapin
    Clonalité
    • 166
    • 55
    Polyclonal
    Conjugué
    • 110
    • 18
    • 15
    • 14
    • 14
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MAP1LC3A est non-conjugé
    Application
    • 199
    • 95
    • 74
    • 47
    • 33
    • 32
    • 29
    • 14
    • 14
    • 14
    • 11
    • 10
    • 9
    • 6
    • 5
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    Full-length recombinant Human LC3
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3A Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Autre désignation
    LC3 (MAP1LC3A Produits)
    Synonymes
    anticorps ATG8E, anticorps LC3, anticorps LC3A, anticorps MAP1ALC3, anticorps MAP1BLC3, anticorps 1010001H21Rik, anticorps 4922501H04Rik, anticorps LC3a, anticorps MGC69006, anticorps zgc:77094, anticorps MGC89867, anticorps MAP1LC3A, anticorps map1lc3a, anticorps microtubule associated protein 1 light chain 3 alpha, anticorps microtubule-associated protein 1 light chain 3 alpha, anticorps microtubule associated protein 1 light chain 3 alpha S homeolog, anticorps MAP1LC3A, anticorps Map1lc3a, anticorps map1lc3a.S, anticorps map1lc3a
    Sujet
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-IISynonyms: Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3A, MAP1 light chain 3-like protein 1, MAP1A / 1B light chain 3 A, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1LC3A, Microtubule-associated protein 1 light chain 3 alpha, Microtubule-associated proteins 1A/1B light chain 3A
    ID gène
    84557
    NCBI Accession
    NM_032514
    Pathways
    Autophagy
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