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ATG4B anticorps (N-Term)

ATG4B Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449637
  • Antigène Voir toutes ATG4B Anticorps
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Épitope
    • 21
    • 17
    • 15
    • 13
    • 13
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-53, N-Term
    Reactivité
    • 117
    • 44
    • 28
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 115
    • 4
    Lapin
    Clonalité
    • 113
    • 6
    Polyclonal
    Conjugué
    • 52
    • 10
    • 9
    • 9
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATG4B est non-conjugé
    Application
    • 99
    • 41
    • 27
    • 27
    • 23
    • 15
    • 13
    • 13
    • 11
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Purification
    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
    Immunogène
    KLH conjugated synthetic peptide between 23~53 amino acids from the N-terminal region of Human APG4B Genename: ATG4B
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG4B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Autre désignation
    APG4B / ATG4B (ATG4B Produits)
    Synonymes
    anticorps apg4b, anticorps APG4B, anticorps AUTL1, anticorps 2510009N07Rik, anticorps AW048066, anticorps Apg4b, anticorps Atg4bl, anticorps Autl1, anticorps Aut2b2, anticorps autophagy related 4B cysteine peptidase, anticorps autophagy-related 4b, anticorps Peptidase family C54 protein, anticorps cysteine protease ATG4B, anticorps ATG4 autophagy related 4 homolog B (S. cerevisiae), anticorps autophagy related 4B, cysteine peptidase, anticorps autophagy related 4B, cysteine peptidase L homeolog, anticorps ATG4B, anticorps Atg4b, anticorps AT3G59950, anticorps Tsp_08582, anticorps Tsp_11599, anticorps atg4b, anticorps atg4b.L
    Sujet
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.Synonyms: AUT-like 1 cysteine endopeptidase, AUTL1, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, Cysteine protease ATG4B, KIAA0943
    Poids moléculaire
    44309 Da
    ID gène
    23192
    NCBI Accession
    NP_037457
    Pathways
    Autophagy
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