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CLEC7A anticorps (Middle Region)

CLEC7A Reactivité: Humain, Souris, Rat WB, IHC (p), IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449932
  • Antigène Voir toutes CLEC7A Anticorps
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Épitope
    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 58
    • 37
    • 5
    • 1
    Humain, Souris, Rat
    Hôte
    • 40
    • 19
    • 19
    Lapin
    Clonalité
    • 41
    • 32
    Polyclonal
    Conjugué
    • 26
    • 11
    • 11
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CLEC7A est non-conjugé
    Application
    • 44
    • 38
    • 25
    • 23
    • 8
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    17 amino acid synthetic peptide near the center of Human CLEC7A
    Isotype
    IgG
    Top Product
    Discover our top product CLEC7A Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Autre désignation
    CLEC7A / Dectin-1 (CLEC7A Produits)
    Synonymes
    anticorps CLEC7A, anticorps BGR, anticorps Clecsf12, anticorps beta-GR, anticorps CANDF4, anticorps CLECSF12, anticorps DECTIN1, anticorps Clec7b, anticorps RGD1565140, anticorps C-type lectin domain containing 7A, anticorps C-type lectin domain family 7, member a, anticorps CLEC7A, anticorps Clec7a
    Sujet
    CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1
    ID gène
    64581
    NCBI Accession
    NP_922938
    Pathways
    Activation of Innate immune Response
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