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CARD14 anticorps (C-Term)

CARD14 Reactivité: Humain IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449966
  • Antigène Voir toutes CARD14 Anticorps
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    Épitope
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 33
    • 21
    • 4
    Humain
    Hôte
    • 29
    • 3
    • 1
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CARD14 est non-conjugé
    Application
    • 24
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Purification
    Affinity Chromatography purified via peptide column
    Immunogène
    14 amino acid synthetic peptide near the carboxy terminus of Human CARMA2
    Isotype
    IgG
    Top Product
    Discover our top product CARD14 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    Autre désignation
    CARD14 / CARMA2 (CARD14 Produits)
    Synonymes
    anticorps BIMP2, anticorps CARMA2, anticorps PRP, anticorps PSORS2, anticorps PSS1, anticorps Bimp2, anticorps caspase recruitment domain family member 14, anticorps caspase recruitment domain family, member 14, anticorps CARD14, anticorps Card14
    Sujet
    CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA2 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kB activation. When expressed in cells, this protein activated NF-kB and induced the phosphorylation of BCL10 Alternative splicing of CARMA2 results in isoforms that possess differential effects on NF-kB activation and endoplasmic reticulum stress-induced cell death.Synonyms: CARD-containing MAGUK protein 2, Caspase recruitment domain-containing protein 14
    ID gène
    79092
    NCBI Accession
    NP_077015
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