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ATG2B anticorps (N-Term)

ATG2B Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1449993
  • Antigène Tous les produits ATG2B
    ATG2B (Autophagy Related 2B (ATG2B))
    Épitope
    • 14
    • 10
    • 5
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 26
    • 10
    • 2
    Humain
    Hôte
    • 26
    Lapin
    Clonalité
    • 26
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp ATG2B est non-conjugé
    Application
    • 20
    • 16
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B
    Isotype
    IgG
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ATG2B (Autophagy Related 2B (ATG2B))
    Autre désignation
    ATG2B (ATG2B Produits)
    Synonymes
    anticorps C14orf103, anticorps 2410024A21Rik, anticorps AI047755, anticorps AI503411, anticorps AW558123, anticorps C030004M05Rik, anticorps C630028L02Rik, anticorps mKIAA4067, anticorps autophagy related 2B, anticorps ATG2B, anticorps Atg2b
    Sujet
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.Synonyms: Autophagy related 2 homolog B
    Poids moléculaire
    229 kDa
    ID gène
    55102
    NCBI Accession
    NP_060506
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