APBA1 anticorps (N-Term)

N° du produit ABIN1450013

Détail du produit anti-APBA1 anticorps

Antigène: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APBA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near the amino terminus of Human APBA1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur APBA1

Antigène: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Autre désignation: APBA1 / MINT1 (APBA1 Produits)

Synonymes: anticorps APBA1, anticorps 6430513E09Rik, anticorps Lin-10, anticorps Mint, anticorps Mint1, anticorps Urop11, anticorps X11, anticorps X11alpha, anticorps D9S411E, anticorps LIN10, anticorps MINT1, anticorps X11A, anticorps X11ALPHA, anticorps amyloid beta precursor protein binding family A member 1, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1b, anticorps ketopantoate reductase, anticorps 2-dehydropantoate 2-reductase, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1 (X11), anticorps amyloid beta (A4) precursor protein-binding, family A, member 1, anticorps amyloid beta (A4) precursor protein binding, family A, member 1, anticorps APBA1, anticorps apba1b, anticorps apbA1, anticorps apba1, anticorps Apba1

Sujet: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.Synonyms: Adapter protein X11alpha, Amyloid beta A4 precursor protein-binding family A member 1, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1

Poids moléculaire: 92 kDa

ID gène: 320

NCBI Accession: NP_001154

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport