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MCM6 anticorps (AA 562-821)

MCM6 Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022687
  • Antigène Voir toutes MCM6 Anticorps
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Épitope
    • 12
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 562-821
    Reactivité
    • 56
    • 23
    • 17
    • 9
    • 7
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 46
    • 6
    • 4
    Lapin
    Clonalité
    • 51
    • 5
    Polyclonal
    Conjugué
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MCM6 est non-conjugé
    Application
    • 43
    • 33
    • 20
    • 15
    • 10
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Séquence
    SIDRVYSLDD IRRYLLFARQ FKPKISKESE DFIVEQYKHL RQRDGSGVTK SSWRITVRQL ESMIRLSEAM ARMHCCDEVQ PKHVKEAFRL LNKSIIRVET PDVNLDQEEE IQMEVDEGAG GINGHADSPA PVNGINGYNE DINQESAPKA SLRLGFSEYC RISNLIVLHL RKVEEEEDES ALKRSELVNW YLKEIESEID SEEELINKKR IIEKVIHRLT HYDHVLIELT QAGLKGSTEG SESYEEDPYL VVNPNYLLED
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 562-821 of human MCM6 (NP_005906.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
    Autre désignation
    MCM6 (MCM6 Produits)
    Synonymes
    anticorps CG4039, anticorps DmMCM6, anticorps DmeMCM6, anticorps Dmel\\CG4039, anticorps MCM6, anticorps McM6, anticorps fs(1)K1214, anticorps mcm6, anticorps MCG40308, anticorps Mis5, anticorps P105MCM, anticorps Mcmd6, anticorps mis5, anticorps mmcm6, anticorps ASP-l1, anticorps D1Wsu22e, anticorps Minichromosome maintenance 6, anticorps DNA replication licensing factor MCM6, anticorps minichromosome maintenance complex component 6, anticorps minichromosome maintenance complex component 6 L homeolog, anticorps DNA replication licensing factor mcm-6, anticorps Mcm6, anticorps TP02_0113, anticorps PVX_114735, anticorps CMU_027970, anticorps MCM6, anticorps mcm6.L, anticorps mcm-6
    Sujet
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.,MCM6,MCG40308,Mis5,P105MCM,Epigenetics & Nuclear Signaling,MCM6
    Poids moléculaire
    92 kDa
    ID gène
    4175
    UniProt
    Q14566
    Pathways
    Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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