This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
anticorps KCNA5, anticorps kcna5, anticorps ATFB7, anticorps HCK1, anticorps HK2, anticorps HPCN1, anticorps KV1.5, anticorps PCN1, anticorps Kv1.5, anticorps Kv1, anticorps potassium voltage-gated channel subfamily A member 5, anticorps potassium channel, voltage gated shaker related subfamily A, member 5, anticorps potassium voltage-gated channel, shaker-related subfamily, member 5, anticorps KCNA5, anticorps kcna5, anticorps Kcna5
Sujet
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. [provided by RefSeq].