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PBX4 anticorps (AA 201-320) (Alexa Fluor 350)

PBX4 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN1693705
  • Antigène Voir toutes PBX4 Anticorps
    PBX4 (Pre-B-Cell Leukemia Homeobox 4 (PBX4))
    Épitope
    • 14
    • 3
    • 2
    • 1
    • 1
    AA 201-320
    Reactivité
    • 19
    • 2
    • 1
    Humain
    Hôte
    • 18
    • 2
    Lapin
    Clonalité
    • 19
    • 1
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PBX4 est conjugé à/à la Alexa Fluor 350
    Application
    • 18
    • 12
    • 12
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PBX4
    Isotype
    IgG
    Top Product
    Discover our top product PBX4 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PBX4 (Pre-B-Cell Leukemia Homeobox 4 (PBX4))
    Autre désignation
    PBX4 (PBX4 Produits)
    Synonymes
    anticorps PBX4, anticorps 2410015M21Rik, anticorps AI429113, anticorps AW045266, anticorps Edg4, anticorps PBX homeobox 4, anticorps pre B cell leukemia homeobox 4, anticorps PBX4, anticorps Pbx4
    Sujet

    Synonyms: 2410015M21Rik, AI429113, AW045266, Edg4, Endothelial dferentiation, lysophosphatidic acid G protein coupled receptor 4, Homeobox protein PBX4, OTTMUSP00000045221, PBX4, PBX4_HUMAN, pre-B-cell leukemia homeobox 4, Pre-B-cell leukemia transcription factor 4.

    Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

    ID gène
    80714
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