K-RAS anticorps (GTPase Kras) (AA 13-41) (HRP)

Details for Product anti-GTPase Kras Antibody No. ABIN1711989, Fournisseur: Connectez-vous pour afficher
Antigène
  • Kras2
  • c-Ki-ras
  • p21
  • C-K-RAS
  • CFC2
  • K-RAS2A
  • K-RAS2B
  • K-RAS4A
  • K-RAS4B
  • KI-RAS
  • KRAS1
  • KRAS2
  • NS
  • NS3
  • RASK2
  • SIIR
  • pp21
  • 0610011M09Rik
  • BC011290
  • P21
  • AI929937
  • K-ras
  • Ki-ras
  • Kras-2
  • p21B
  • ras
  • wu:fa04e08
  • wu:fc14b12
  • wu:fc23g10
  • wu:fj89d12
  • zgc:85725
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
  • GTPase KRas
  • Kirsten rat sarcoma viral oncogene
  • Kirsten rat sarcoma viral oncogene homolog
  • transcription elongation factor A (SII)-like 1
  • KRAS
  • NCU03616
  • PGTG_03066
  • Tsp_02666
  • Tsp_01642
  • rask
  • Kras
  • TCEAL1
  • Tceal1
  • kras
Épitope
AA 13-41
28
15
14
12
10
9
9
6
5
4
4
4
4
4
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
237
77
56
10
8
8
5
4
4
4
4
4
4
3
2
2
2
1
1
1
Hôte
Lapin
172
74
Clonalité
Polyclonal
Conjugué
Cet anticorp K-RAS est conjugé à/à la HRP
12
12
10
7
7
7
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
168
100
79
44
32
30
30
26
15
13
8
4
4
2
1
1
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human P21
Isotype IgG
Purification Purified by Protein A.
Autre désignation P21
Sujet

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Subcellular location: Cytoplasm, Nucleus

Synonyms: P21, CIP1, SDI1, WAF1, CAP2, CDKN1, MDA-6, p21CIP1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, CDKN1A, MDA6, PIC1

ID gène 1026
UniProt P38936
Domaine de recherche Cancer, Cell Cycle
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
Avez-vous cherché autre chose?