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PIK3 gamma anticorps (HRP)

Détails pour le produit réf. ABIN1711992, Fournisseur: Connectez-vous pour afficher
Antigène
Reactivité
Humain, Souris, Rat (Rattus)
44
44
44
Hôte
Lapin
44
Clonalité
Polyclonal
Conjugué
HRP
3
3
3
3
3
3
3
3
3
3
3
3
3
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
8
8
Options
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Immunogène KLH conjugated synthetic peptide derived from human PIK3 gamma
Isotype IgG
Purification Purified by Protein A.
Sujet

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

Subcellular location: Cytoplasm


Synonyms: PK3CG_HUMAN, PI 3 Kinase catalytic subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma,
ID gène 5294
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months