Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) anticorps (HRP)

Détails pour le produit réf. ABIN1711998, Fournisseur: Connectez-vous pour afficher
Antigène
  • si:dkey-119m7.6
  • WISP3
  • CCN6
  • LIBC
  • PPAC
  • PPD
  • ENSMUSG00000062074
  • Gm735
  • WISP-3
  • RGD1564120
  • WNT1 inducible signaling pathway protein 3
  • wisp3
  • WISP3
  • Wisp3
Reactivité
Humain, Souris, Rat (Rattus)
48
14
14
Hôte
Lapin
47
1
Clonalité
Polyclonal
Conjugué
HRP
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
24
22
19
13
11
4
2
2
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human WISP3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Wisp3 (WISP3 Antibody Extrait)
Sujet

Wnt-induced secreted protein (WISP)-1, WISP-2 and WISP-3 are members of the CCN family of growth factors, which include connective tissue growth factor (CTGF) and Cyr61. WISP-1, WISP-2 and WISP-3 share significant sequence similarity, including four conserved cysteine-rich domains, and they are believed to function as dimers in their active forms. WISP-1 expression is observed in various tissues including adult heart, kidney and spleen, while WISP-2 expression predominates in skeletal muscle, colon and ovary. Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, and they are also more highly expressed in human colon tumors, suggesting that these proteins may participate in tumor development. WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization.

Synonyms: CCN 6, CCN family member 6, CCN6, CYR61, LIBC, Lost in inflammatory breast cancer tumor suppressor protein, MGC125987, MGC125988, MGC125989, OTTHUMP00000040421, PPAC, PPD, UNQ462/PRO790/PRO956, WISP 3, WISP-3, WISP3, WISP3_HUMAN, WNT 1 inducible signaling pathway protein 3, Wnt 1 signaling pathway protein 3, WNT1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3 precursor, WNT1-inducible-signaling pathway protein 3.

ID gène 8838
Domaine de recherche Stem Cells, Wnt
Pathways Growth Factor Binding
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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