ABLIM3 anticorps (Actin Binding LIM Protein Family, Member 3) (HRP)

Details for Product anti-ABLIM3 Antibody No. ABIN1712000, Fournisseur: Connectez-vous pour afficher
Antigène
  • AW990719
  • D930036B08Rik
  • RGD1565118
  • actin binding LIM protein family, member 3
  • ABLIM3
  • Ablim3
Reactivité
Humain, Souris, Rat (Rattus)
41
15
15
Hôte
Lapin
37
4
Clonalité
Polyclonal
Conjugué
Cet anticorp ABLIM3 est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
28
14
14
4
2
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human ABLIM3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Ablim3 (ABLIM3 Antibody Extrait)
Sujet

The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

Synonyms: abLIM-3, Ablim3, ABLM3_HUMAN, Actin binding LIM protein 3, Actin binding LIM protein family member 3, Actin-binding LIM protein 3, Actin-binding LIM protein family member 3, HMFN1661, KIAA0843.

ID gène 22885
Domaine de recherche Signaling, Cytoskeleton, Microfilaments
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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