CYP2A6 anticorps (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6) (HRP)

Details for Product anti-CYP2A6 Antibody No. ABIN1712030, Fournisseur: Connectez-vous pour afficher
Antigène
  • CYP2A
  • CYP2A6
  • CPA6
  • CYP2A3
  • CYPIIA6
  • P450C2A
  • P450PB
  • cytochrome P450 2A19
  • cytochrome P450, family 2, subfamily A, polypeptide 6
  • CYP2A19
  • CYP2A6
Reactivité
Humain, Souris, Rat (Rattus)
107
25
23
5
2
2
1
1
1
1
1
1
Hôte
Lapin
64
43
Clonalité
Polyclonal
Conjugué
Cet anticorp CYP2A6 est conjugé à/à la HRP
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
89
19
18
13
13
11
10
2
2
2
2
1
1
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human CYP2A/Cytochrome P450 2A6
Isotype IgG
Purification Purified by Protein A.
Autre désignation Cyp2a/Cytochrome P450 2a6 (CYP2A6 Antibody Extrait)
Sujet

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds (1). Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies (2). NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle (3,4). NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5 (5,6). NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin (7). Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively (8).

Synonyms: Coumarin 7 hydroxylase, Coumarin 7-hydroxylase, CP2A6_HUMAN, CPA6, CYP2A, CYP2A3, CYP2A6, CYPIIA6, Cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450 subfamily IIA phenobarbital inducible polypeptide 6, Cytochrome P450I, Cytochrome P450, family 2 subfamily A polypeptide 6, Flavoprotein linked monooxygenase, P450C2A, P450PB, Xenobiotic monooxygenase.

ID gène 1548
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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