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Destrin anticorps (AA 75-165) (HRP)

DSTN Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712033
  • Antigène Voir toutes Destrin (DSTN) Anticorps
    Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 75-165
    Reactivité
    • 45
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 5
    Lapin
    Clonalité
    • 40
    • 5
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Destrin est conjugé à/à la HRP
    Application
    • 39
    • 21
    • 19
    • 16
    • 13
    • 13
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Monkey
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Destrin
    Isotype
    IgG
    Top Product
    Discover our top product DSTN Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
    Autre désignation
    Destrin (DSTN Produits)
    Synonymes
    anticorps ACTDP, anticorps ADF, anticorps bA462D18.2, anticorps DSTN, anticorps LOC100190417, anticorps adf, anticorps actdp, anticorps ba462d18.2, anticorps 2610043P17Rik, anticorps AU042046, anticorps Dsn, anticorps corn1, anticorps sid23p, anticorps destrin, anticorps destrin, actin depolymerizing factor, anticorps destrin, anticorps destrin, actin depolymerizing factor S homeolog, anticorps DSTN, anticorps dstn, anticorps Dstn, anticorps dstn.S
    Sujet

    Synonyms: 2610043P17Rik, ACTDP, Actin depolymerizing factor, Actin-depolymerizing factor, ADF, AU042046, bA462D18.2, corn1, DEST_HUMAN, Destrin actin depolymerizing factor, Destrin, DSN, Dstn, Sid 23, sid23p.

    Background: Actin-depolymerizing factor (ADF), also known as destrin, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. The Actin-depolymerizing activity of ADF is reversibly controlled by changes in KCl concentration but is insensitive to calcium concentration. ADF depolymerizes F-Actin by interacting directly with F-Actin protomers. ADF shares 71 % sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. The difference in the function of ADF and Cofilin results from the subtle difference in their amino acid sequence rather than possible differences in posttranslational modifications. As a result of different cleavage sites on ADF and Cofilin, the proteins differ in their overall tertiary folds. Sensitivity to polyphosphoinositides may be a common feature in vitro among Actin-binding proteins such as ADF and Cofilin that can bind to G-Actin and regulate the state of Actin polymerization. ADF and Cofilin are Actin-depolymerizing proteins whose activities are possibly regulated by their phosphorylation/dephosphorylation.

    ID gène
    11034
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