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DOCK2 anticorps (Dedicator of Cytokinesis 2) (AA 500-550) (HRP)

Détail du produit anti-DOCK2 anticorps No. ABIN1712036, Fournisseur: Connectez-vous pour afficher
Antigène
  • AI662014
  • AW122239
  • CED-5
  • Hch
  • MBC
  • dedicator of cytokinesis 2
  • dedicator of cyto-kinesis 2
  • DOCK2
  • LOC100231624
  • dock2
  • Dock2
Épitope
AA 500-550
14
6
4
3
2
2
2
2
2
1
Reactivité
Humain, Souris, Rat (Rattus)
48
26
17
1
1
1
1
1
Hôte
Lapin
37
10
2
Clonalité
Polyclonal
Conjugué
Cet anticorp DOCK2 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
27
13
11
7
7
2
2
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human DOCK2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Dock2 (DOCK2 Antibody Extrait)
Sujet

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Subcellular location: Cytoplasm


Synonyms: Dedicator of cytokinesis protein 2, DOCK2, KIAA0209
ID gène 1794
UniProt Q92608
Domaine de recherche Stem Cells, Hematopoietic Progenitors, Cytoskeleton, Microfilaments
Indications d'application IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months