DUOXA2 anticorps (Dual Oxidase Maturation Factor 2) (HRP)

Details for Product anti-DUOXA2 Antibody No. ABIN1712038, Fournisseur: Connectez-vous pour afficher
Antigène
  • DUOXA1
  • DUOXA2
  • SIMNIPHOM
  • TDH5
  • 9030623N16Rik
  • RGD1560628
  • dual oxidase maturation factor 1-like
  • dual oxidase maturation factor 2
  • DUOXA1L
  • DUOXA2
  • Duoxa2
Reactivité
Humain, Souris, Rat (Rattus)
34
14
14
Hôte
Lapin
34
Clonalité
Polyclonal
Conjugué
Cet anticorp DUOXA2 est conjugé à/à la HRP
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
20
14
13
3
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human DUOXA2
Isotype IgG
Purification Purified by Protein A.
Autre désignation DUOXA2 (DUOXA2 Antibody Extrait)
Sujet

DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family. Expressed specifically in thyroid and salivary glands, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH). Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth. The gene encoding DUOXA2 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Subcellular location: Extracellular

Synonyms: Dual oxidase activator 2, Dual oxidase maturation factor 2, SIMNIPHOM, TDH5, DOXA2_HUMAN, Dual oxidase maturation factor-2, Dual oxidase activator 2..

ID gène 405753
Pathways Thyroid Hormone Synthesis
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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