FDPS anticorps (Farnesyl Diphosphate Synthase) (HRP)

Details for Product anti-FDPS Antibody No. ABIN1712050, Fournisseur: Connectez-vous pour afficher
Antigène
  • CG12389
  • DmFPPS
  • DmFPPSase
  • DmFPS
  • Dmel\\CG12389
  • FPS
  • fpps
  • fps
  • l(2)k06103
  • v(2)k03514
  • NCU01175.1
  • 16.m00760
  • DDBDRAFT_0206220
  • DDBDRAFT_0215017
  • DDB_0206220
  • DDB_0215017
  • FPPS
  • Ac2-125
  • (2E
  • 6030492I17Rik
  • AI256750
  • Fdpsl1
  • mKIAA1293
  • Farnesyl pyrophosphate synthase
  • farnesyl diphosphate synthase
  • farnesyl pyrophosphate synthetase
  • FDP synthase
  • Farnesyl pyrophosphate synthetase
  • farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
  • farnesyl diphosphate synthetase
  • farnesyl pyrophosphate synthase1
  • Fpps
  • fdps
  • MGG_08649
  • TP03_0857
  • Tb09.160.4300
  • NCU01175
  • BBOV_I000120
  • fps
  • fpps
  • FDPS
  • Fdps
  • fps1
Reactivité
Humain, Souris, Rat (Rattus)
94
32
25
2
2
2
2
1
1
1
1
Hôte
Lapin
93
7
1
Clonalité
Polyclonal
Conjugué
Cet anticorp FDPS est conjugé à/à la HRP
6
5
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
44
29
14
13
9
7
5
3
2
2
2
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human FDPS
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fdps (FDPS Antibody Extrait)
Sujet

FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.

Synonyms: 2E,6E farnesyl diphosphate synthase, 6E-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyl diphosphate synthetase, Farnesyl pyrophosphate synthase, Farnesyl pyrophosphate synthetase, Fdps, FPP synthase, FPP synthetase, FPPS, FPPS_HUMAN, FPS, Geranyltranstransferase.

ID gène 2224
Domaine de recherche Cancer, Metabolism
Pathways Regulation of Muscle Cell Differentiation
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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